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Hollis, Thomas
One or more keywords matched the following items that are connected to
Hollis, Thomas
Item Type
Name
Academic Article
Functional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome.
Academic Article
The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Academic Article
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
Academic Article
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.
Concept
Autoimmune Diseases of the Nervous System
Academic Article
The TREX1 C-terminal region controls cellular localization through ubiquitination.
Academic Article
The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.
Academic Article
SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.
Search Criteria
Autoimmune Diseases of the Nervous System